Skip to main content

Amyotrophic Lateral Sclerosis (ALS) and cannabis in Colorado

The state currently does not list this condition as qualifying, and the program does not provide open-ended physician discretion to add conditions. Verify with the state regulator, because programs change.

Not on the qualifying list
✗ No
LEGAL
2 oz usable + 6 plants …
POSSESSION
$25/yr
STATE FEE
5–14 d
TIMELINE
Not on the qualifying list. The state currently does not list this condition as qualifying, and the program does not provide open-ended physician discretion to add conditions. Verify with the state regulator, because programs change.

Colorado statute and program

The Colorado Medical Marijuana Registry is the operating authority for Colorado patient certification. The authoritative legal text is: Colorado Department of Public Health & Environment: Medical Marijuana Registry. The program portal is at Colorado Medical Marijuana Registry.

What the evidence says about cannabis and Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that destroys motor neurons in the brain and spinal cord, leading to loss of voluntary muscle control. Symptoms typically include muscle weakness, spasticity, fasciculations, dysphagia, and respiratory compromise. Most patients survive 2–5 years from diagnosis.

For the full evidence base, including the NASEM tier, randomized trial summaries, and symptom-domain breakdown, read the mmjnow Amyotrophic Lateral Sclerosis (ALS) page.

How to qualify in Colorado

The Colorado Medical Marijuana Registry requires the following registration steps for a Amyotrophic Lateral Sclerosis (ALS) patient (or any qualifying diagnosis):

  1. Get a physician certification from a Colorado-licensed practitioner. Under Colo. Const. Art. XVIII §14 (Amendment 20 of 2000), any Colorado-licensed physician (MD or DO), advanced practice registered nurse with prescriptive authority, or physician assistant may certify a patient for one of the enumerated debilitating medical conditions: cancer, glaucoma, HIV/AIDS, MS, cachexia, severe pain, severe nausea, seizures, severe and persistent muscle spasms, PTSD, autism spectrum disorder, or any condition for which a physician could prescribe an opioid (added 2019, HB 19-1028).
  2. Apply through the CDPHE Medical Marijuana Registry portal. The patient creates an account in the Colorado Department of Public Health and Environment (CDPHE) Medical Marijuana Registry online portal, uploads the physician certification, a Colorado driver license or state ID, and a passport-style photograph. Patients aged 18 to 20 must have two physician certifications (a safeguard added in 2016).
  3. Pay the $25 state registration fee. The Colorado medical marijuana registry card fee is $25 per year (reduced from $90 in 2017). Indigent patients (defined as receiving state-provided medical assistance or SSDI) pay no fee under §25-1.5-106. Caregivers register separately at no additional state fee but undergo a background check.
  4. Receive the card and purchase from a Colorado dispensary. Colorado medical marijuana registry cards (the "red card") are typically issued within 5 to 7 business days of complete application. With the card, patients may purchase up to 2 ounces every 24 hours (cap removable on physician recommendation) and cultivate up to 6 plants for personal medical use. Adult-use retail is legal statewide for adults 21+; medical patients retain reduced taxation (no special tax versus the 15% adult-use excise tax), access to higher-potency concentrates, and the 2-ounce daily purchase limit versus the 1-ounce adult-use limit.
State registration fee
$25
Physician visit (typical)
$100–$200
Certification to card
5–14 days
Out-of-state patients
Not eligible
Minors
Eligible with caregiver

For full Colorado registration steps, fees, and reciprocity rules, see the Colorado cannabis-laws page.

ICD-10 code

A certifying physician documenting Amyotrophic Lateral Sclerosis (ALS) for the Colorado medical cannabis program will typically record ICD-10 G12.21 or SNOMED-CT 86044005 in the patient's record. The state registry does not itself collect ICD-10 codes in most programs, but the physician's chart is the audit trail if the certification is later reviewed.

Frequently asked questions

Does Colorado list Amyotrophic Lateral Sclerosis (ALS) as a qualifying condition for medical cannabis?

No. Colorado's qualifying-condition list does not currently include Amyotrophic Lateral Sclerosis (ALS), and the state's program does not give physicians open-ended discretion to add conditions outside the list. Patients with Amyotrophic Lateral Sclerosis (ALS) in Colorado have limited in-state pathways under the medical program as written. Options to verify and pursue include: petitioning the state regulator to add the condition (where the statute permits public petitions); consulting a physician about whether a co-occurring listed condition could support certification; or reviewing whether the state's program is undergoing legislative expansion. Colorado program rules change, so verify the current list with the regulator before drawing a final conclusion.

How do I get a Colorado medical marijuana card for Amyotrophic Lateral Sclerosis (ALS)?

Because Colorado does not currently list Amyotrophic Lateral Sclerosis (ALS) as a qualifying condition, a card for Amyotrophic Lateral Sclerosis (ALS) alone may not be obtainable in-state under the program rules as written. Step one is finding a physician licensed in Colorado who is registered with Colorado Medical Marijuana Registry and willing to evaluate Amyotrophic Lateral Sclerosis (ALS) cases. Step two is collecting your records (diagnosis documentation, treatment history, and the ICD-10 code your physician will use) and bringing them to the certification visit. Step three is the physician's certification through the state registry, followed by the patient registration application, state fee, and waiting period before the card is issued. Colorado does not honor out-of-state cards, so the certification process has to originate inside the state. The state minimum patient age is 18; minors generally require a parent or legal guardian to act as caregiver. The authoritative source for the current process is the Colorado Medical Marijuana Registry site at https://cdphe.colorado.gov/medicalmarijuana; the state updates fees, forms, and physician registration rules periodically.

What does the evidence say about cannabis for Amyotrophic Lateral Sclerosis (ALS)?

For Amyotrophic Lateral Sclerosis (ALS), evidence is described as limited (a small number of supportive studies, often underpowered or focused on narrow symptom domains). The mmjnow condition page for Amyotrophic Lateral Sclerosis (ALS) lays out the current evidence base, including the citations underlying that evidence tier — typically the National Academies of Sciences, Engineering, and Medicine consensus reports, federal agency guidance, and peer-reviewed reviews. Evidence quality is independent of state law: a state can list a condition for which evidence is limited, and a state can decline to list a condition for which evidence is strong. Patients deciding whether to pursue medical cannabis for Amyotrophic Lateral Sclerosis (ALS) should review the underlying evidence (linked on the condition page) and discuss expected benefit, dosing, and risk with a clinician familiar with both Amyotrophic Lateral Sclerosis (ALS) and cannabinoid pharmacology. Cannabis is not a substitute for evidence-based first-line treatments for Amyotrophic Lateral Sclerosis (ALS); the evidence position above describes whether trial data supports its use, not whether it should replace standard care.

Sources

  1. Colorado Department of Public Health & Environment: Medical Marijuana Registryaccessed May 14, 2026
  2. Colorado Marijuana Enforcement Division (MED): Adult-Use Rulesaccessed May 14, 2026
  3. NASEM: The Health Effects of Cannabis and Cannabinoids (2017)accessed May 15, 2026
  4. ALS Association: Cannabis and ALSaccessed May 15, 2026